| Name |
Title of Research |
Period of Funding |
Claude Asselin
Co-applicant:Fernand-Pierre Gendron
University of Sherbrooke
|
Role of C/EBP transcription factors and deacetylation in intestinal inflammation |
2011-2014 |
Michael Blennerhassett
Queen's University
|
Understanding and preventing stricturing in Crohn’s disease |
2011-2014 |
Andre Buret
University of Calgary
|
Interactions of Campylobacter jejuni with the intestinal microflora and host response |
2011-2014 |
Kris Chadee
University of Calgary
|
Defining the mechanisms of epithelial dysfuntion in Muc2-/- mice
|
2011-2014 |
Scott Gray-Owen
Co-applicant: Philip Sherman
University of Toronto |
AIEC Engagement of CEACAM6: Defining the Link to Crohn's Disease |
2011-2014 |
Kevan Jacobson
BC Children's Hospital |
Strengthening the Epithelial barrier Reduces Susceptibility to IBD |
2011-2014 |
Waliul Khan
McMaster University
|
Target inhibition of serotonin signaling as a strategy to reduce the severity of colitis |
2011-2014 |
Wallace MacNaughton
University of Calgary |
Protease-activated receptor 2 promotes the resolution of inflammation
|
2011-2014 |
Elaine Petrof
Queen's University
|
L. plantarum blocks inflammation in colitis Immunomodualtion of intestinal function by Vitamin D |
2011-2014 |
John Wallace
McMaster University
|
Integration of Anti-Inflammatory Pathways in IBD |
2011-2014 |
Paul Beck
Co-applicant: Subrata Ghosh
University of Calgary |
|
The NLRP3-inflammasome is a key regulator of intestinal homeostasis
2010-2013 |
Francois Boudreau
Co-applicants: Nathalie Perreault and Julie Carrier
University of Sherbrooke |
Blocking inflammatory genes expression during inflammatory bowel disease |
2010-2013 |
Stephen Girardin
University of Toronto |
The NOD-like receptor IL-22 signaling pathway in the defense of the intestinal lining |
2010-2013 |
Paul Kubes
University of Calgary |
Role of the Adapter Molecule MyD88 and the Protein Molecule TRIF in IBD |
2010-2013 |
Dana Philpott
University of Toronto |
Nod proteins in intestinal homeostasis |
2010-2013 |
Nathalie Rivard
University of Sherbrooke |
Role of the phosphate-removing enzyme, SHP-2, in intestinal inflammation |
2010-2013 |
Marika Sarfati
Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM) |
Characterization of disease-causing dendritic cells in Crohn's disease |
2010-2013 |
Mark Silverberg
Mount Sinai Hospital |
Genetic markers of outcomes in Crohn's disease |
2010-2013 |
Bruce Vallance
University of British Columbia |
Modeling Intestinal Fibrosis in Crohn's Disease
|
2010-2013 |
Stephen Vanner
Queen’s University |
Investigation of new pain targets for treating patients with inflammatory bowel disease |
2010-2013 |
Elena Verdu
McMaster University |
Sensing of microflora and colitis |
2010-2013 |
Premysl Bercik
Co-applicant: Stephen Collins
McMaster University |
I
Intestinal microbiota and the increased sensitivity to colitis in depression
|
2009-2012 |
Kenneth Croitoru
University of Toronto |
Studies of the induction and regulation of colitis in a mouse model
Studies of the induction and regulation of colitis in a mouse model
All That Glitters Gala, Toronto, Grant in Aid of Research |
2009-2012 |
Fernand-Pierre Gendron
Universite de Sherbrooke |
Re-visiting P2Y nucleotide receptors as a cure for IBD
Role of epithelial cells P2Y receptors in the dysfunction of the intestinal mucosa during inflammation |
2009-2012
Progress Report 1 |
Alan Lomax
Queen's University |
Neuroimmune interactions during inflammatory bowel diseases
Sympathetic neuropathy in IBD: causes and consequences
|
2009-2012
Progress Report 1 |
Karen Madsen
Univesirty of Alberta |
Bacterial DNA and gut function
Bacterial DNA and gut homeostasis |
2009-2012 |
Derek McKay
University of Calgary
|
The inhibition of colitis by helminth infection
Helminth Infection, Alternatively Activated Macrophages and the Inhibition of Colitis |
2009-2012
Progress Report 1 |
David Sigalet
Alberta Children's Hospital |
Immune signaling pathways of the GLP2 protein in the inflamed intestine
Immune signaling pathways of the Glugacon Like Peptide 2 in the inflamed intestine
M&M Meat Shops Grant in Aid of Research |
2009-2012
Progress Report 1 |
Emma Allen-Vercoe
University of Guelph
|
Does a disease-causing bacterium from the mouth also cause problems in the gut for IBD patients?
Interactions of Fusobacterium nucleatum with intestinal epithelial cells: Implication for disease exacerbation in IBD
The Grocery Foundation Grant in Aid of Research |
2009-2012
Progress Report 1
|
Claude Asselin
University of Sherbrooke |
The intestinal epithelial cell response to inflammation
Role of C/EBP transcription factors and deacetylation in intestinal inflammation |
2008-2011
Summary
Progress Report 1 |
Michael Blennerhassett
Queen’s University |
Why does inflammation cause nerve damage in IBD, and how can we prevent this?
Neuronal survival and axon regeneration in intestinal inflammation |
2008-2011
Summary |
Richard Fedorak
Co-applicants: Carolyn Slupsky and Beate Sydora
University of Alberta |
Finding a urine test that will diagnose IBD
The IBD Metablome Project: NMR Metabolic Analysis to Identify IBD and the microbe-genetype Relationship
Electronics Industry Hockey Tournament Innovations in IBD Research Award |
2008-2010
Summary
Progress Report 1
|
Brett Finlay
University of British Columbia |
The role of inflammation and the microbiota using different models: Exploring the interplay between host and microbiota during colitis
The role of the microbiota in infectious colitis and fibrosis |
2008-2011
Summary
Progress Report 1
Progress Report 2 |
Scott Gray-Owen
Co-applicant: Philip Sherman
University of Toronto |
Tickling the receptor: Defining how bacteria linked to Crohn's disease penetrate the gut surface
AIEC engagement of CEACAM6: Defining the link to Crohn's disease
Federated Health Charities’ Grant in Aid of Research |
2008-2011
Summary
Progress Report 1 |
Nicola Jones
Co-applicants: Dana Philpott, John Brumell, and Mark Silverberg
Hospital for Sick Children |
Determining how the ATG16L1 gene favors the development of Crohn disease
The role of ATG16L1 in Crohn's disease |
2008-2011
Summary
Progress Report 1 |
Waliul Khan
McMaster University |
How the hormone serotonin influences gut inflammation
Endocrinological regulation of gut inflammation by serotonin (5-hydroxytryptamine; 5-HT) |
2008-2011
Summary
Progress Report 1 |
Wallace MacNaughton
University of Calgary |
Role of proteases and their receptors in IBD
Mechanisms of protease-induced inflammation in IBD |
2008-2011
Summary
Progress Report 1 |
Elaine Petrof
Queen’s University |
Use of probiotic products as a strategy to block intestinal inflammation
Effect of probiotic conditioned media on a mouse model of inflammatory colitis
Fay Shapiro Cutler Legacy Grant
|
2008-2011
Summary
Progress Report 1
Progress Report 2
|
Mark Silverberg
Co-applicants: Gordon Greenberg, Robin McLeod, Denis Krause, Wei Xu
Mount Sinai Hospital |
Inherited and environmental factors that contribute to the development of inflammation of the pouch after surgery for ulcerative colitis
Genetic, serological, and microbial factors related to patterns of illeal Inflammation |
2008-2011
Summary
Progress Report 1
Progress Report 2
|
Laura Sly
Child and Family Research Institute |
Altering immune cell function in inflammatory bowel disease
Macrophage phenotype in inflammatory bowel disease
M&M Meat Shops Legacy Grant |
2008-2011
Summary
Progress Report 1
Progress Report 2 |
Martin Storr
Co-applicant: Keith Sharkey
University of Calgary |
Treatment of IBD with cannabinoids, looking for a cure
Cannabinoids in colitis
Healthpartners Grant in Aid of Research |
2008-2011
Summary
Progress Report 1
Progress Report 2 |
Ali Ahmad
St. Justine Hospital |
Role of NK Receptors and their Ligands in the immunopathogenesis of Crohn’s Disease
M&M Meat Shops Grant in Aid of Research |
2007-2010
Progress Report 1
Progress Report 2
Final Report |
François Boudreau
Universite de Sherbrooke |
Role of Transcriptional Effectors of the TGFB Superfamily During Intestinal Inflammatory Response
The Grandey Family Foundation Grant in Aid of Research
|
2007-2010
Progress Report 1
Progress Report 2 |
|
Andre G. Buret
University of Calgary
|
Disruptions of epithelial integrity in the pathogenesis of IBD: The effects of C. jejuni. |
2007-2010
Progress Report 1
Progress Report 2
Final Report
|
Kris Chadee
University of Calgary |
Role of prostaglandin E(2) in modulating epithelial barrier function |
2007-2010
Progress Report 1
Progress Report 2
Final report |
Jeroen Marc Daniel De Buck
University of Calgary |
Proteomic identification of human and animal Mycobacterium avium subsp. Paratuberculosis strains by mass spectrometry |
2007-2008
Final Report |
Christophe Faure
Sainte-Justine Hopital |
Regulation and role of PSA-NCAM in enteric nervous system in TNBS-induced colitis |
2007-2008
Progress Report 1 |
Richard Fedorak
University of Alberta |
The IBD Metabolome Project: NMR Metabolomic Analysis to Identify IBD and the Microbe-Genotype Relationship |
2007-2008
|
Stephen Girardin
University of Toronto |
New insights into the detection of peptidoglycan by Nod2/CARD15: implications for Crohn’s disease |
2007-2010
Progress Report 1 |
Kevan Jacobson
BC’s Children’s Hospital |
Intestinal Barrier Responses, neuropeptides and IBD |
2007-2010
Progress Report 1
Final Report |
Denis Krause
University of Manitoba |
Role of Bacteroides spp. and Escherichia coli in inflammatory bowel disease
All That Glitters Gala, Winnipeg, Grant in Aid of Research |
2007-2010
Progress Report 1
Progress Report 2
Final Report |
Andrew James Macpherson
McMaster University |
Mechanisms of normal intestinal lamina propria CD4 responses that ensure mutualism with commensal intestinal bacteria |
2007-2010
Progress Report 1 |
Robin McLeod
Mount Sinai Hospital |
Post Operative Recurrence in paediatric Crohn’s disease: Influence of Molecular Factors |
2007-2010
Progress Report 1
Progress Report 2 |
Mark Ropeleski
Queen’s University |
Intestinal Epithelial anti-apoptotic signalling and healing: novel roles for IL-11 in inflammation |
2007-2010
Progress Report 1
Progress Report 2 |
Philip Sherman
Hospital for Sick Children |
Role of Probiotics in the management of experimental inflammatory bowel diseases
Fay Shapiro Cutler Grant in Aid of Research |
2007-2010
Progress Report 1
Progress Report 2
Final Report
|
Katherine Siminovitch
Mt Sinai Hospital |
Characterization of susceptibility genes/molecules for inflammatory bowel disease
The Kerry and Simone Vickar Family Foundation Grant in Aid of Research |
2007-2010
Progress Report 1
Progress Report 2
|
Bruce Vallance
University of British Columbia |
Goblet Cell Mediators and their Impact on Mucosal Protection and Susceptibility to Colitis |
2007-2010
Progress Report 1
Progress Report 2
Final Report
|
Stephen Vanner
Queen’s University |
Novel Pain Mechanisms in IBD |
2007-2010
Progress Report 1
|
John Wallace
University of Calgary |
Resolution of Colitis: A Translational Study |
2007-2010
Progress Report 1
Progress Report 2
|
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